New challenges for Bioinformatics and Computational Chemistry in NanoBiotechnology

After the progress made during the Genomics Era, Bioinformatics was tasked to support the first flow of information generated by Nanobiotechnology at the early stages of development. This challenge requires the adaptation of classical bioinformatics tools, and also computational chemistry tools, to store, standardize, analyze and visualize the information generated in Nanobiotechnology. Therefore, bioinformatics and computational chemistry have been merged to develop a new sub-discipline called Nanoinformatics. This review depicts some new requirements such as the development of new tools and technologies that are critical for the design, modeling, simulation and visualization of Nanosystems that arisen during the accelerated evolution of Nanobiotechnology applied in life science. The knowledge obtained at the nano-scale implies the answer of new questions and the development of new concepts in different fields. Thus, it requires the implementation of collaborative networks and the creation of web platforms for sharing and discussing the knowledge generated in nanobiotechnology. For instance, the implementation of new databases schemes suitable to storage and to process data generated in nanobiotechnology (physical, chemical and biological properties of nanoparticles), will be key elements to derive the information needed to unleash the promise behind this convergent field. Therefore, in this work, we will also review some applications of Nanobiotechnology in life science, discussing how this application can generate new requirements for diverse scientific field such as Bioinformatics and Computational Chemistry. Keyword: Bioinformatics, Molecular Simulation, Nanobiotechnology, Nanoinformatics, Nanomedicine.